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Date: April 29, 2024 Mon

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Results for urine testing

7 results found

Author: Wish, Eric D.

Title: The Maryland Adult Offender Population Urine Screening (OPUS) Program - Final Report

Summary: In 2005, CESAR piloted an innovative cost-effective method to measure drug use trends in offenders in Maryland, using urine specimens already collected and tested for a small panel of drugs by the Division of Parole and Probation (DPP). The 2005 OPUS study sampled 299 specimens obtained from adult parolees and probationers in six counties in Maryland (Baltimore City, Baltimore, Howard, Prince George’s, Charles and Washington counties) and retested the specimens for an expanded panel of 30 drugs. The findings indicated considerable promise of the OPUS methodology for providing the state with information regarding the availability and use of drugs by offenders. The current study used the OPUS methodology to obtain 1,061 specimens from the three Maryland DPP labs that process urine specimens submitted from 55 DPP collection sites. These specimens were sent to a laboratory for testing of an extended panel of 31 drugs. As we found in the prior pilot study, the most common drugs detected were marijuana, cocaine, benzodiazepines, and morphine. Again, we found almost no evidence of methamphetamine use and that most PCP positives came from offenders in Prince George’s County. On the other hand, a larger percentage of buprenorphine positives were detected (5% vs. 13%, p<.001) than we found in 2005, suggesting greater use of this relatively newly prescribed drug in Maryland. Considerable geographic differences were found in the patterns of drugs detected across Maryland. Only 4% of the tested specimens were found to test positive solely for a drug in the expanded screen. It therefore appears that the current five drug DPP screen identifies 96% of all recent drug users. The OPUS methodology may provide states with a relatively quick and low cost method for monitoring drug trends in offenders.

Details: College Park, MD: Center for Substance Abuse Research (CESAR), University of Maryland, 2009. 70p.

Source: Internet Resource: Accessed June 20, 2012 at http://www.goccp.maryland.gov/msac/documents/bjag-2005-1080.pdf

Year: 2009

Country: United States

URL: http://www.goccp.maryland.gov/msac/documents/bjag-2005-1080.pdf

Shelf Number: 125393

Keywords:
Adult Offenders (Maryland)
Drug Offenders
Drug Testing
Evaluative Studies (Maryland)
Urinalysis (Maryland)
Urine Testing

Author: Wish, Eric D.

Title: The Maryland Adult Offender Population Urine Screening (OPUS) Program: Final Report

Summary: In 2005, CESAR piloted an innovative cost-effective method to measure drug use trends in offenders in Maryland, using urine specimens already collected and tested for a small panel of drugs by the Division of Parole and Probation (DPP). The 2005 OPUS study sampled 299 specimens obtained from adult parolees and probationers in six counties in Maryland (Baltimore City, Baltimore, Howard, Prince George’s, Charles and Washington counties) and retested the specimens for an expanded panel of 30 drugs. The findings indicated considerable promise of the OPUS methodology for providing the state with information regarding the availability and use of drugs by offenders. The current study used the OPUS methodology to obtain 1,061 specimens from the three Maryland DPP labs that process urine specimens submitted from 55 DPP collection sites. These specimens were sent to a laboratory for testing of an extended panel of 31 drugs. As we found in the prior pilot study, the most common drugs detected were marijuana, cocaine, benzodiazepines, and morphine. Again, we found almost no evidence of methamphetamine use and that most PCP positives came from offenders in Prince George’s County. On the other hand, a larger percentage of buprenorphine positives were detected (5% vs. 13%, p<.001) than we found in 2005, suggesting greater use of this relatively newly prescribed drug in Maryland. Considerable geographic differences were found in the patterns of drugs detected across Maryland. Only 4% of the tested specimens were found to test positive solely for a drug in the expanded screen. It therefore appears that the current five drug DPP screen identifies 96% of all recent drug users. The OPUS methodology may provide states with a relatively quick and low cost method for monitoring drug trends in offenders.

Details: College Park, MD: Center for Substance Abuse Research (CESAR), University of Maryland, College Park, 2009. 70p.

Source: Internet Resource: Accessed July 2, 2012 at: http://www.goccp.maryland.gov/msac/documents/bjag-2005-1080.pdf

Year: 2009

Country: United States

URL: http://www.goccp.maryland.gov/msac/documents/bjag-2005-1080.pdf

Shelf Number: 125441

Keywords:
Drug Abuse and Addiction
Drug Abuse and Crime
Drug Offenders
Urine Testing

Author: Wish, Eric D.

Title: Community Drug Early Warning System: The CDEWS Pilot

Summary: This report describes a pilot test of the Community Drug Early Warning System (CDEWS) in three jurisdictions in the Washington, DC and Richmond, VA, Metropolitan Areas. CDEWS was designed to provide rapid information about emerging drug use in local communities by sampling urine specimens already obtained and tested for a limited panel of drugs by local criminal justice agencies and retesting them for a larger panel of drugs. The anonymous specimens were sent to an independent laboratory for testing for a panel of more than 30 licit and illicit drugs including 12 synthetic cannabinoid (SC) metabolites. The results demonstrated that CDEWS could be successfully implemented in diverse criminal justice populations, including arrestees, probationers and parolees, and drug court participants. Most important, CDEWS proved its utility for uncovering emerging drugs. SCs were detected in the specimens from all participating sites in the District of Columbia, Maryland, and Virginia. Furthermore, all of the SC positive specimens contained one or two of the metabolites (UR-144 and XLR-11) recently identified and added to the federal schedule of prohibited SC metabolites after this study began. Additional analyses of the CDEWS results identified areas of Washington, DC, where the SC positive specimens were more concentrated and where future studies of its use and availability could be focused. The report concludes with research implications of the findings and next steps for implementing CDEWS in other sites.

Details: Washington, DC: Executive Office of the President, 2013. 80p.

Source: Internet Resource: Accessed May 16, 2015 at: https://www.whitehouse.gov/sites/default/files/finalreport_with_cover_09172013.pdf

Year: 2013

Country: United States

URL: https://www.whitehouse.gov/sites/default/files/finalreport_with_cover_09172013.pdf

Shelf Number: 135655

Keywords:

Drug Abuse and Addiction
Drug Control Policy
Drug Enforcement
Drug Testing
Illicit Drugs
Urine Testing

Author: Wish, Eric D.

Title: Community Drug Early Warning System: The CDEWS-2 Replication Study

Summary: The Community Drug Early Warning System (CDEWS) provides rapid information about emerging drug use in local communities by sampling anonymous urine specimens already collected and tested, and ready to be discarded by local criminal justice programs. CDEWS re- tests the specimens for an expanded panel of more than 75 drugs. The most dramatic finding from the first study, CDEWS-1, completed in September 2013, was the identification of specific synthetic cannabinoids (SC) used by adult arrestee and parole/probation populations in the Washington, DC and Richmond, VA Metropolitan Areas. SC metabolites were actually equally or more likely to be detected in specimens that had passed the local criminal justice system (CJS) drug tests than in those that failed, suggesting that people were using them to avoid detection by the routine CJS testing screens. This second report on CDEWS (CDEWS-2) replicates the CDEWS results for adult parolees/probationers in Washington, DC, and studies new adult and/or juvenile criminal justice populations from Washington, DC (juveniles), Denver, Colorado (drug court adults), and Tampa, Florida (juveniles). A total of 1,026 specimens from these populations were tested as part of the CDEWS-2 study. The CDEWS-2 urinalyses showed dramatic changes from the SC metabolites detected the prior year in CDEWS-1, and shows substantial differences in SC found from site to site. For the CDEWS-2 study, we interviewed toxicologists and other experts to determine the most important drugs, including new psychoactive substances (NPS), to include on our testing panel. This shows the value of interviewing experts in order to update the CDEWS test panel to include newly discovered SC metabolites. A large number of specimens tested positive for the metabolites added during CDEWS-2. About 50% of the 21-30 year old male probationers from DC who had passed the local more limited CJS screen and about 1 in 5 of all tested juveniles in DC at all ages, from 13-17, tested positive for SC. The SC metabolites detected varied by population and site; for example, all SC positive specimens from Tampa juveniles contained only one metabolite, UR-144, but only 71% of the SC positive specimens from DC juveniles and 53% of SC positives from adults in the Denver drug court contained UR-144. In fact, among DC juveniles, 8 SC metabolites were found and among Denver adults 10 SC metabolites were found. Testing for designer stimulants was suspended after all subsamples for the 4 populations tested negative for these drugs. The CDEWS-2 results attest to the value of expanded testing of specimens already collected by local CJS drug testing programs and the difficulties inherent in keeping up with the constantly evolving nature of NPS. The results suggest that many adults and juveniles in local CJS drug testing programs likely turn to SC to avoid detection. It is also likely that programs using similar protocols to test urine specimens in other contexts, such as schools, hospitals and treatment programs are missing SC use in their populations, leading to lost opportunities for diagnosis and intervention. These risks are especially dangerous for youths being exposed to new and constantly changing NPS at an early age. Future CDEWS studies of these populations might help to address these issues.

Details: Washington, DC: Office of National Drug Control Policy Executive Office of the President, 2015. 100p.

Source: Internet Resource: Accessed August 8, 2015 at: https://www.whitehouse.gov/sites/default/files/ondcp/policy-and-research/finalreport_4_8_15v3.pdf

Year: 2015

Country: United States

URL: https://www.whitehouse.gov/sites/default/files/ondcp/policy-and-research/finalreport_4_8_15v3.pdf

Shelf Number: 136354

Keywords:
Drug Abuse and Addiction
Drug Control Policy
Drug Enforcement
Drug Testing
Illicit Drugs
Urine Testing

Author: Wish, Eric D.

Title: Community Drug Early Warning System (CDEWS-3): Maryland - Site 4 of 4

Summary: The Community Drug Early Warning System (CDEWS) provides timely information about emerging drug use in criminal justice populations in local communities by collecting and re-testing urine specimens already obtained and tested for a limited panel of drugs by local criminal justice testing programs. CDEWS or local staff sample specimens that are ready to be discarded and send them to an independent laboratory for testing for an expanded panel of over 150 drugs. By using already collected de-identified urine specimens, CDEWS is able to provide a relatively quick and inexpensive snapshot of the types of drugs recently used by participating populations. The CDEWS methodology has now been piloted in twelve jurisdictions and the results are provided in five reports already released by the Office of National Drug Control Policy (ONDCP). This report presents findings from adult parolees and probationers in a single jurisdiction -- Maryland -- as part 4 of 4 sites for the third CDEWS Study, called CDEWS-3. This study was conducted somewhat differently from prior CDEWS studies. This is because we wanted to replicate the findings from a study we had conducted in Maryland in 2008. And second, because of the opioid epidemic in Maryland, the State asked us to collect and analyze a separate large sample of specimens statewide that had tested positive for opiates by the laboratory used by the Maryland Division of Parole and Probation (DPP). With the strong support of the DPP, we collected two samples of specimens: the Maryland Regional Sample (N=288) and the Opiate Positive (Opiate+) Sample (N=202 statewide). Specimens were classified as CJS+ (tested positive for any drug) or CJS- (tested negative for all drugs) according to the results from the DPP laboratory's 4-drug screen. The findings from the Maryland Regional Sample indicated that most of the persons who had tested positive for one of the drugs in the CDEWS larger test panel had also tested positive for one of the four drugs in the DPP drug screen. However, approximately one in ten CJS+ specimens also contained antidepressants, synthetic cannabinoids (SC), methadone and/or other licit pharmaceutical opioids, drugs not tested for by the limited DPP screen. The additional drugs the CDEWS lab detected may not have practical significance for the DPP, given that most of these specimens did test positive for a drug in the DPP's limited screen. It is not possible to tell from the urinalyses if the persons taking the licit drugs were doing so legally under a physician's supervision. In contrast, 15% of the specimens that the DPP screen indicated did not contain a drug (CJS-) contained an opioid. Methadone and buprenorphine were among the opioids most found in CJS specimens and it is possible that these persons were receiving treatment with these drugs. Antidepressants were identified in as many CJS- specimens as CJS+ specimens (9%). SC was found in CJS- specimens but these metabolites were less common than in CJS+ specimens. These results suggest that in this population, persons were unlikely to be using SC to avoid detection by the standard DPP tests. The comparisons of probationers/parolees in this study and our earlier study in 2008 show considerable agreement in the drugs detected. The primary changes were a decline in cocaine (36% to 17%) and buprenorphine (15% to 7%) and an increase in codeine (3% to 13%) among CJS+ specimens. The increase in codeine positives may be the result of the increased sensitivity of the tests used in the current study. The results from the Opiate+ Sample strongly indicated that probationers/parolees who had tested positive for opiates by the DPP screen were likely to be using a variety of legal and illegal opioids in addition to non-opioid drugs. About one in three also used cocaine, one fifth used marijuana and/or benzodiazepines and about one quarter used a prescription opioid other than morphine or codeine. These results therefore have important implications for the testing used by physicians and diagnosticians who need to know if patients are using other drugs. Use of multiple opioids at the same time may lead to serious health complications and even death. We also conducted special analyses of the combined specimens found in either sample to be positive for fentanyl, synthetic cannabinoids, or codeine. Perhaps some of the most meaningful results in this study were those showing the large number of opioid and non-opioid drugs found in the fentanyl+ specimens. The 21 specimens positive for fentanyl each contained an average of 5 different drugs, most prominently morphine, codeine, 6-MAM (heroin), cocaine, and/or hydromorphone. The findings for fentanyl+ specimens were similar to those described above for the entire sample of Opiate+ specimens and our recent study of 136 persons who died of a fentanyl related overdose in New Hampshire. It is clear that probationers/parolees in Maryland who screen positive for any opioids are likely to be using a variety of other opioid and non-opioid drugs. These findings suggest that treatment will be more effective if one identifies and focuses on the totality of drugs the person may be using. Our analysis of the combined sample of all specimens positive for SC supported the findings from our previous CDEWS studies that found multiple SC metabolites in specimens. Surprisingly, specimens from the current study often contained both new and older generation SC metabolites. Given the unpredictable composition of synthetic cannabinoids (also known as Spice or K2) being marketed, it is not possible for users to know what chemicals they are consuming and to predict the effects. SC was less likely to be found in the Maryland samples compared to other CDEWS study samples, and few persons who tested CJS- in the Maryland Regional Sample were found to test positive for SC. Probationers in Maryland may therefore be less likely than other populations CDEWS has studied to use SC to avoid screening positive by the CJS test screens, which do not typically test for SC. We also found that 70% of the Opiate+ specimens contained codeine and that codeine was found across the state. In addition, codeine was detected in 81% of fentanyl+ specimens from the combined Opiate+ and Maryland Regional samples. Acetylcodeine, which metabolizes into codeine, is often produced as an impurity of illicit heroin synthesis, which may explain the large percentage of specimens positive for codeine given that almost all of the specimens also contained morphine. It is also possible that some of the codeine positives were the result of the direct use of codeine. We suspected that some of the codeine detected might have been caused by the use of "Purple Drank", a mixture of codeine syrup and promethazine typically sold as a cough suppressant, that has been reported in Maryland. However, only 4% of the codeine positive specimens contained promethazine. Given that the half-life of promethazine is longer than that of codeine, one would expect to have detected promethazine in these specimens had "Purple Drank" been the source of the codeine. It is also possible that the codeine may have resulted from codeine extracted from pills containing the drug. Additional research is needed to learn more about the codeine that was detected in 60% or more of probationers across all regions of Maryland and how the use of codeine may relate to the State's current opioid epidemic.

Details: Washington, DC: Office of National Drug Control Policy Executive Office of the President, 2017. 57p.

Source: Internet Resource: Accessed November 29, 2017 at: https://ndews.umd.edu/sites/ndews.umd.edu/files/finalreport_cdews3_mdapproved.pdf

Year: 2017

Country: United States

URL: https://ndews.umd.edu/sites/ndews.umd.edu/files/finalreport_cdews3_mdapproved.pdf

Shelf Number: 148578

Keywords:
Drug Abuse and Addiction
Drug Control Policy
Drug Enforcement
Drug Offenders
Drug Testing
Illicit Drugs
Parolees
Probationers
Urine Testing

Author: Wish, Eric D.

Title: Community Drug Early Warning System (CDEWS-3): Honolulu, Hawaii - Site 1 of 4

Summary: The Community Drug Early Warning System (CDEWS) provides timely information about emerging drug use in criminal justice populations in local communities by collecting and re‐testing urine specimens already obtained and tested for a limited panel of drugs by local criminal justice testing programs. CDEWS or local staff sample specimens that are ready to be discarded and send them to an independent laboratory for testing for an expanded panel of drugs. By using already collected de‐identified urine specimens, CDEWS can provide a relatively quick and inexpensive snapshot of the types of drugs recently used by participating populations. The CDEWS methodology has been implemented in five jurisdictions and the results are contained in two reports already released by the Office of National Drug Control Policy (Wish et al., 2013, 2015). We introduce here a new report format that contains the findings from a single jurisdiction - the Hawaii's Opportunity Probation with Enforcement (HOPE) and General Supervision (GS) probationer populations in Honolulu, Hawaii - as part 1 of 4 sites for the third CDEWS Study, called CDEWS‐3. In 2004, Judge Steven Alm launched the HOPE program in Hawaii. HOPE enrolls higher risk felony probationers with serious criminal histories and extensive substance abuse histories in a program that includes frequent urine drug monitoring coupled with brief jail sanctions for drug violations (The Institute for Behavior and Health, Inc., 2015). With Judge Alm's strong support, local staff were able to provide anonymous urine specimens previously collected from a sample of adult male probationers from the HOPE program (n=194) and the neighboring GS probation program (n=143), which were then sent to the CDEWS independent laboratory for expanded testing. While the onsite screens used by the HOPE and GS probation programs only tests for 6 drugs, the CDEWS independent laboratory tested for over 150 legal and illegal drugs. The expanded testing showed that the current onsite test screens used by these programs had identified most of the drug users in the HOPE and GS probationer programs. The most common drugs found were methamphetamine and amphetamine. Any additional legal and illegal drugs detected by the CDEWS independent laboratory were primarily detected in specimens that had previously tested positive for at least one of the drugs in the standard local onsite screens. The major exception was methamphetamine, which was detected in a minority of the specimens that had tested negative for all drugs, including methamphetamine, by the onsite criminal justice system (CJS) drug screens. Subsequent analyses suggested that this under‐detection was because the onsite screens for methamphetamine were less sensitive than the tests utilized by the CDEWS independent laboratory. We had hypothesized that the HOPE probationers might be more likely than GS probationers to turn to synthetic cannabinoids (SCs) to evade detection, because of the HOPE program's focus on sanctioning people for "dirty" urines. While SCs were found only in specimens that had tested negative by the CJS onsite drug screens, few specimens (2% or less) from HOPE or GS probationers tested positive for SC. However, the SC metabolites that were detected were later generation SC metabolites recently added to the CDEWS‐3 laboratory test panel. None of these later generation metabolites could have been detected by either the onsite or laboratory SC screens used by the GS and HOPE probation programs at the time of the study. This finding attests to the need for jurisdictions to routinely update their test panels for synthetic drugs, whose formulations tend to change rapidly. Although SC use was found in some probationers in this jurisdiction in Hawaii, SCs may not be as large a problem as was found in some prior CDEWS studies. Nevertheless, the Hawaii HOPE and GS programs may want to consider expanding their SC test panel to include the newer SC metabolites (AB‐PINACA, 5F‐AB‐PINACA, AB‐CHMINACA (metab 4), 5F‐AMB) that were detected in their populations.

Details: Washington, DC: Office of National Drug Control Policy, Executive Office of the President, 2016 37p.

Source: Internet Resource: Accessed November 29, 2017 at: https://obamawhitehouse.archives.gov/sites/default/files/ondcp/policy-and-research/cdews3_hawaii_final.pdf

Year: 2016

Country: United States

URL: https://obamawhitehouse.archives.gov/sites/default/files/ondcp/policy-and-research/cdews3_hawaii_final.pdf

Shelf Number: 148580

Keywords:
Drug Abuse and Addiction
Drug Control Policy
Drug Enforcement
Drug Offenders
Drug Testing
Urine Testing

Author: Wish, Eric D.

Title: Community Drug Early Warning System (CDEWS-3): Ohio -- Site 2 of 4

Summary: The Community Drug Early Warning System (CDEWS) provides timely information about emerging drug use in criminal justice populations in local communities by collecting and re‐testing urine specimens already obtained and tested for a limited panel of drugs by criminal justice testing programs. CDEWS or local staff sample specimens that are ready to be discarded and send them de‐ identified to an independent laboratory for testing for an expanded panel of drugs. The CDEWS methodology has been implemented previously in five jurisdictions with non‐prison populations (Wish et al., 2013; Wish et al., 2015). This report describes the first CDEWS study of prison inmates, conducted in the Belmont and Ross Correctional Institutions for adult males in Ohio. This report is the second of 4 reports that are part of the third CDEWS Study, CDEWS‐3. Urine drug testing is conducted in these facilities on the basis of the inmate's assignment to one of three test groups: Random, For Cause, and treatment Program testing. Specimens are tested by the correctional institution for a panel of 8 drugs. Specimens that had tested positive (CJS+) or negative (CJS‐) for any drug by the prison drug screen were selected from each of the test groups for inclusion in the study. A total of 108 usable specimens were obtained from Belmont and 85 specimens from Ross. The most dramatic findings from this study involved the detection of two types of prescription drugs in both institutions, buprenorphine, a prescribed opioid used to treat substance use disorder for opioids, and antidepressants. Buprenorphine is not prescribed for treatment in these institutions and it is not clear how much of the antidepressants detected were prescribed by the physicians at the prison. While marijuana use was detected in these institutions, it is noteworthy that not a single specimen tested positive for a synthetic cannabinoid. In contrast to other criminal populations studied by CDEWS in other locations, there was no evidence of synthetic cannabinoid use to avoid detection by the prison's drug testing program. This study demonstrated that the CDEWS methodology could be adapted for prison settings. While the use of buprenorphine and marijuana was already being detected by these institutions' testing programs, the extensive use of antidepressants uncovered may be a new finding.

Details: Washington, DC: Office of National Drug Control Policy Executive Office of the President, 2016. 36p.

Source: Internet Resource: Accessed December 6, 2017 at: https://ndews.umd.edu/sites/ndews.umd.edu/files/pubs/finalreport-cdews3-oh-v31-final-for-distribution.pdf

Year: 2016

Country: United States

URL: https://ndews.umd.edu/sites/ndews.umd.edu/files/pubs/finalreport-cdews3-oh-v31-final-for-distribution.pdf

Shelf Number: 148740

Keywords:
Drug Abuse and Addiction
Drug Control Policy
Drug Enforcement
Drug Testing
Illicit Drugs
Urine Testing